The average home in the San Francisc Bay Area cost $1.3m so you need $260,000 in cash to make a 20% down payment plus about $25,000 for closing costs. The principle and interest payment would be about $5,000 at 4% interest; property taxes would be around $1,200 a month; and insurance would be $150 monthly so your total PITI is $6,350. To qualify for this loan the lender would want you to make at least $200,000 a year.